Current opinion in genetics & development
Perrimon N, Stern C.
PMID: 10449360
Curr Opin Genet Dev. 1999 Aug;9(4):387-9. doi: 10.1016/s0959-437x(99)80058-6.
No abstract available.
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Perrimon N, Stern C. Pattern formation and developmental mechanisms unresolved issues of pattern formation . Curr Opin Genet Dev. 1999;9(4):387-9doi: 10.1016/s0959-437x(99)80058-6.
Perrimon, N., & Stern, C. (1999). Pattern formation and developmental mechanisms unresolved issues of pattern formation . Current opinion in genetics & development, 9(4), 387-9. https://doi.org/10.1016/s0959-437x(99)80058-6
Perrimon, and Stern. "Pattern formation and developmental mechanisms unresolved issues of pattern formation ." Current opinion in genetics & development vol. 9,4 (1999): 387-9. doi: https://doi.org/10.1016/s0959-437x(99)80058-6
Perrimon N, Stern C. Pattern formation and developmental mechanisms unresolved issues of pattern formation . Curr Opin Genet Dev. 1999 Aug;9(4):387-9. doi: 10.1016/s0959-437x(99)80058-6. PMID: 10449360.
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Current opinion in genetics & development
Makalowski W, Wolfsberg T.
PMID: 10980421
Curr Opin Genet Dev. 2000 Oct;10(5):467.
A selection of World Wide Web sites relevant to papers published in this issue of Current Opinion in Genetics & Development.
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Makalowski W, Wolfsberg T. Differentiation and gene regulation. Web alert. Curr Opin Genet Dev. 2000;10(5):467
Makalowski, W., & Wolfsberg, T. (2000). Differentiation and gene regulation. Web alert. Current opinion in genetics & development, 10(5), 467.
Makalowski, and Wolfsberg. "Differentiation and gene regulation. Web alert." Current opinion in genetics & development vol. 10,5 (2000): 467.
Makalowski W, Wolfsberg T. Differentiation and gene regulation. Web alert. Curr Opin Genet Dev. 2000 Oct;10(5):467. PMID: 10980421.
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Current opinion in genetics & development
Haiman CA, Stram DO.
PMID: 20359883
Curr Opin Genet Dev. 2010 Jun;20(3):330-5. doi: 10.1016/j.gde.2010.02.007. Epub 2010 Mar 30.
Incidence rates for many cancers differ markedly by race/ethnicity and furthering our understanding of the genetic and environmental causes of such disparities is a scientific and public health need. Genome-wide association studies (GWAS) are widely acknowledged to provide important...
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Haiman CA, Stram DO. Exploring genetic susceptibility to cancer in diverse populations. Curr Opin Genet Dev. 2010;20(3):330-5doi: 10.1016/j.gde.2010.02.007.
Haiman, C. A., & Stram, D. O. (2010). Exploring genetic susceptibility to cancer in diverse populations. Current opinion in genetics & development, 20(3), 330-5. https://doi.org/10.1016/j.gde.2010.02.007
Haiman, Christopher A, and Stram, Daniel O. "Exploring genetic susceptibility to cancer in diverse populations." Current opinion in genetics & development vol. 20,3 (2010): 330-5. doi: https://doi.org/10.1016/j.gde.2010.02.007
Haiman CA, Stram DO. Exploring genetic susceptibility to cancer in diverse populations. Curr Opin Genet Dev. 2010 Jun;20(3):330-5. doi: 10.1016/j.gde.2010.02.007. Epub 2010 Mar 30. PMID: 20359883; PMCID: PMC4196678.
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Current opinion in genetics & development
Green MR, Stillman B.
PMID: 8791494
Curr Opin Genet Dev. 1996 Apr 01;6(2):139-40. doi: 10.1016/s0959-437x(96)80041-4.
No abstract available.
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Green MR, Stillman B. Chromosomes and expression mechanisms. Curr Opin Genet Dev. 1996;6(2):139-40doi: 10.1016/s0959-437x(96)80041-4.
Green, M. R., & Stillman, B. (1996). Chromosomes and expression mechanisms. Current opinion in genetics & development, 6(2), 139-40. https://doi.org/10.1016/s0959-437x(96)80041-4
Green, and Stillman. "Chromosomes and expression mechanisms." Current opinion in genetics & development vol. 6,2 (1996): 139-40. doi: https://doi.org/10.1016/s0959-437x(96)80041-4
Green MR, Stillman B. Chromosomes and expression mechanisms. Curr Opin Genet Dev. 1996 Apr 01;6(2):139-40. doi: 10.1016/s0959-437x(96)80041-4. PMID: 8791494.
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Current opinion in genetics & development
Ankawa R, Fuchs Y.
PMID: 34861514
Curr Opin Genet Dev. 2021 Nov 30;72:53-60. doi: 10.1016/j.gde.2021.10.006. Epub 2021 Nov 30.
The hair follicle is a unique mini organ that undergoes continuous cycles of replenishment. While hair follicle formation was long thought to occur strictly during embryogenesis, it is now becoming increasingly clear that hair follicles can regenerate from the...
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Ankawa R, Fuchs Y. May the best wound WIHN: the hallmarks of wound-induced hair neogenesis. Curr Opin Genet Dev. 2021;72:53-60doi: 10.1016/j.gde.2021.10.006.
Ankawa, R., & Fuchs, Y. (2021). May the best wound WIHN: the hallmarks of wound-induced hair neogenesis. Current opinion in genetics & development, 7253-60. https://doi.org/10.1016/j.gde.2021.10.006
Ankawa, Roi, and Fuchs, Yaron. "May the best wound WIHN: the hallmarks of wound-induced hair neogenesis." Current opinion in genetics & development vol. 72 (2021): 53-60. doi: https://doi.org/10.1016/j.gde.2021.10.006
Ankawa R, Fuchs Y. May the best wound WIHN: the hallmarks of wound-induced hair neogenesis. Curr Opin Genet Dev. 2021 Nov 30;72:53-60. doi: 10.1016/j.gde.2021.10.006. Epub 2021 Nov 30. PMID: 34861514.
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Current opinion in genetics & development
Reitz D, Chan YL, Bishop DK.
PMID: 34343922
Curr Opin Genet Dev. 2021 Dec;71:120-128. doi: 10.1016/j.gde.2021.06.016. Epub 2021 Jul 31.
Members of the RecA family of strand exchange proteins carry out the central reaction in homologous recombination. These proteins are DNA-dependent ATPases, although their ATPase activity is not required for the key functions of homology search and strand exchange....
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Reitz D, Chan YL, Bishop DK. How strand exchange protein function benefits from ATP hydrolysis. Curr Opin Genet Dev. 2021;71:120-128doi: 10.1016/j.gde.2021.06.016.
Reitz, D., Chan, Y. L., & Bishop, D. K. (2021). How strand exchange protein function benefits from ATP hydrolysis. Current opinion in genetics & development, 71120-128. https://doi.org/10.1016/j.gde.2021.06.016
Reitz, Diedre, et al. "How strand exchange protein function benefits from ATP hydrolysis." Current opinion in genetics & development vol. 71 (2021): 120-128. doi: https://doi.org/10.1016/j.gde.2021.06.016
Reitz D, Chan YL, Bishop DK. How strand exchange protein function benefits from ATP hydrolysis. Curr Opin Genet Dev. 2021 Dec;71:120-128. doi: 10.1016/j.gde.2021.06.016. Epub 2021 Jul 31. PMID: 34343922.
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Current opinion in genetics & development
Simoneau A, Zou L.
PMID: 34329853
Curr Opin Genet Dev. 2021 Jul 27;71:92-98. doi: 10.1016/j.gde.2021.07.003. Epub 2021 Jul 27.
The maintenance of genomic integrity relies on the coordination of a wide range of cellular processes and efficient repair of DNA damage. Since its discovery over two decades ago, the ATR kinase has been recognized as the master regulator...
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Simoneau A, Zou L. An extending ATR-CHK1 circuitry: the replication stress response and beyond. Curr Opin Genet Dev. 2021;71:92-98doi: 10.1016/j.gde.2021.07.003.
Simoneau, A., & Zou, L. (2021). An extending ATR-CHK1 circuitry: the replication stress response and beyond. Current opinion in genetics & development, 7192-98. https://doi.org/10.1016/j.gde.2021.07.003
Simoneau, Antoine, and Zou, Lee. "An extending ATR-CHK1 circuitry: the replication stress response and beyond." Current opinion in genetics & development vol. 71 (2021): 92-98. doi: https://doi.org/10.1016/j.gde.2021.07.003
Simoneau A, Zou L. An extending ATR-CHK1 circuitry: the replication stress response and beyond. Curr Opin Genet Dev. 2021 Jul 27;71:92-98. doi: 10.1016/j.gde.2021.07.003. Epub 2021 Jul 27. PMID: 34329853.
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Current opinion in genetics & development
Gnügge R, Symington LS.
PMID: 34329854
Curr Opin Genet Dev. 2021 Jul 27;71:99-105. doi: 10.1016/j.gde.2021.07.004. Epub 2021 Jul 27.
Exposure to environmental mutagens but also cell-endogenous processes can create DNA double-strand breaks (DSBs) in a cell's genome. DSBs need to be repaired accurately and timely to ensure genomic integrity and cell survival. One major DSB repair mechanism, called...
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Gnügge R, Symington LS. DNA end resection during homologous recombination. Curr Opin Genet Dev. 2021;71:99-105doi: 10.1016/j.gde.2021.07.004.
Gnügge, R., & Symington, L. S. (2021). DNA end resection during homologous recombination. Current opinion in genetics & development, 7199-105. https://doi.org/10.1016/j.gde.2021.07.004
Gnügge, Robert, and Symington, Lorraine S. "DNA end resection during homologous recombination." Current opinion in genetics & development vol. 71 (2021): 99-105. doi: https://doi.org/10.1016/j.gde.2021.07.004
Gnügge R, Symington LS. DNA end resection during homologous recombination. Curr Opin Genet Dev. 2021 Jul 27;71:99-105. doi: 10.1016/j.gde.2021.07.004. Epub 2021 Jul 27. PMID: 34329854.
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Current opinion in genetics & development
Rees E, Kirov G.
PMID: 33752146
Curr Opin Genet Dev. 2021 Jun;68:57-63. doi: 10.1016/j.gde.2021.02.014. Epub 2021 Mar 19.
Copy number variants (CNVs) at specific loci have been identified as important risk factors for several neuropsychiatric disorders, such as schizophrenia, autism spectrum disorder, intellectual disability (ID) and depression. These CNVs are individually rare (
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Rees E, Kirov G. Copy number variation and neuropsychiatric illness. Curr Opin Genet Dev. 2021;68:57-63doi: 10.1016/j.gde.2021.02.014.
Rees, E., & Kirov, G. (2021). Copy number variation and neuropsychiatric illness. Current opinion in genetics & development, 6857-63. https://doi.org/10.1016/j.gde.2021.02.014
Rees, Elliott, and Kirov, George. "Copy number variation and neuropsychiatric illness." Current opinion in genetics & development vol. 68 (2021): 57-63. doi: https://doi.org/10.1016/j.gde.2021.02.014
Rees E, Kirov G. Copy number variation and neuropsychiatric illness. Curr Opin Genet Dev. 2021 Jun;68:57-63. doi: 10.1016/j.gde.2021.02.014. Epub 2021 Mar 19. PMID: 33752146; PMCID: PMC8219524.
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Current opinion in genetics & development
Fuccillo MV, Pak C.
PMID: 33756113
Curr Opin Genet Dev. 2021 Jun;68:64-70. doi: 10.1016/j.gde.2021.02.010. Epub 2021 Mar 21.
Neurexins are central to trans-synaptic cell adhesion and signaling during synapse specification and maintenance. The past two decades of human genetics research have identified structural variations in the neurexin gene family, in particular NRXN1 copy number variants (CNVs), implicated...
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Fuccillo MV, Pak C. Copy number variants in neurexin genes: phenotypes and mechanisms. Curr Opin Genet Dev. 2021;68:64-70doi: 10.1016/j.gde.2021.02.010.
Fuccillo, M. V., & Pak, C. (2021). Copy number variants in neurexin genes: phenotypes and mechanisms. Current opinion in genetics & development, 6864-70. https://doi.org/10.1016/j.gde.2021.02.010
Fuccillo, Marc V, and Pak, ChangHui. "Copy number variants in neurexin genes: phenotypes and mechanisms." Current opinion in genetics & development vol. 68 (2021): 64-70. doi: https://doi.org/10.1016/j.gde.2021.02.010
Fuccillo MV, Pak C. Copy number variants in neurexin genes: phenotypes and mechanisms. Curr Opin Genet Dev. 2021 Jun;68:64-70. doi: 10.1016/j.gde.2021.02.010. Epub 2021 Mar 21. PMID: 33756113; PMCID: PMC8491281.
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Current opinion in genetics & development
van Wietmarschen N, Nathan WJ, Nussenzweig A.
PMID: 34284257
Curr Opin Genet Dev. 2021 Jul 17;71:34-38. doi: 10.1016/j.gde.2021.06.014. Epub 2021 Jul 17.
One of the goals of precision medicine is to uncover selective vulnerabilities in various cancers. A notable success has been the development of PARP inhibitors for the treatment of breast and ovarian cancers with mutations in BRCA genes. Only...
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van Wietmarschen N, Nathan WJ, Nussenzweig A. The WRN helicase: resolving a new target in microsatellite unstable cancers. Curr Opin Genet Dev. 2021;71:34-38doi: 10.1016/j.gde.2021.06.014.
van Wietmarschen, N., Nathan, W. J., & Nussenzweig, A. (2021). The WRN helicase: resolving a new target in microsatellite unstable cancers. Current opinion in genetics & development, 7134-38. https://doi.org/10.1016/j.gde.2021.06.014
van Wietmarschen, Niek, et al. "The WRN helicase: resolving a new target in microsatellite unstable cancers." Current opinion in genetics & development vol. 71 (2021): 34-38. doi: https://doi.org/10.1016/j.gde.2021.06.014
van Wietmarschen N, Nathan WJ, Nussenzweig A. The WRN helicase: resolving a new target in microsatellite unstable cancers. Curr Opin Genet Dev. 2021 Jul 17;71:34-38. doi: 10.1016/j.gde.2021.06.014. Epub 2021 Jul 17. PMID: 34284257.
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Current opinion in genetics & development
van der Burg KR, Reed RD.
PMID: 33740694
Curr Opin Genet Dev. 2021 Aug;69:82-87. doi: 10.1016/j.gde.2021.02.009. Epub 2021 Mar 17.
Phenotypic plasticity in response to environmental cues is common in butterflies, and is a major driver of butterfly wing pattern diversity. The endocrine signal ecdysone has been revealed as a major modulator of plasticity in butterflies. External cues such...
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van der Burg KR, Reed RD. Seasonal plasticity: how do butterfly wing pattern traits evolve environmental responsiveness?. Curr Opin Genet Dev. 2021;69:82-87doi: 10.1016/j.gde.2021.02.009.
van der Burg, K. R., & Reed, R. D. (2021). Seasonal plasticity: how do butterfly wing pattern traits evolve environmental responsiveness?. Current opinion in genetics & development, 6982-87. https://doi.org/10.1016/j.gde.2021.02.009
van der Burg, Karin Rl, and Reed, Robert D. "Seasonal plasticity: how do butterfly wing pattern traits evolve environmental responsiveness?." Current opinion in genetics & development vol. 69 (2021): 82-87. doi: https://doi.org/10.1016/j.gde.2021.02.009
van der Burg KR, Reed RD. Seasonal plasticity: how do butterfly wing pattern traits evolve environmental responsiveness?. Curr Opin Genet Dev. 2021 Aug;69:82-87. doi: 10.1016/j.gde.2021.02.009. Epub 2021 Mar 17. PMID: 33740694.
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